Reversol
Natural Allies That Fight High Cholesterol
WHAT IT IS:
- A physician-formulated, five-ingredient botanical and mineral complex designed to support healthy cholesterol and triglyceride levels
WHY YOU NEED IT:
- Combines 5 well-studied natural ingredients that work at different points in cholesterol metabolism
- Built around Sytrinol®, a patented citrus and palm-fruit complex, at the full 300 mg dose used in clinical research
- Includes standardized Gugulipid, the resin of the mukul myrrh tree used in Ayurvedic medicine for centuries
- Artichoke extract supports healthy bile flow and the liver's normal handling of cholesterol
- Guar gum, a viscous soluble fiber, works right in the intestine where bile acids are reabsorbed
- Chromium supports normal insulin signaling and healthy glucose and lipid metabolism
- Excellent for patients who want nutritional support alongside diet, exercise, and their regular lipid panel
- Convenient two-capsule daily serving, 30-day supply per bottle
- Not intended for use during pregnancy or nursing.
HOW IT HELPS:
Cholesterol is not made in one place or by one pathway. Your liver manufactures it, your intestine recycles it through bile, and your metabolic hormones decide how much of it circulates. Reversol was designed around that reality: rather than leaning on a single ingredient, it brings together five natural agents that each address a different step.
Sytrinol is the centerpiece. It is a patented blend of polymethoxylated flavones (PMFs) from citrus peel, principally tangeretin and nobiletin, combined with tocotrienols from red palm fruit. These compounds influence cholesterol production inside the cell rather than dietary cholesterol at the table. Sytrinol is the product of more than a decade of research, and the 300 mg daily amount in Reversol is the same dose used in the published human trials, where it was studied for its effects on total cholesterol, LDL, triglycerides, and the LDL-to-HDL ratio. The PMFs also carry meaningful antioxidant activity, which matters because oxidized LDL particles are the ones that damage artery walls.
Artichoke flower extract works from a different angle. Artichoke is rich in caffeoylquinic acids such as chlorogenic acid, along with the bitter compound cynarin, and it has a long history of use as a liver and bile tonic. Bile is how your body actually disposes of cholesterol, so supporting normal bile production supports normal cholesterol clearance. A meta-analysis pooling nine randomized trials in over 700 people found artichoke extract supplementation was associated with meaningful reductions in total cholesterol, LDL, and triglycerides, and later pooled analyses have reported similar findings.
Guar gum is the mechanical partner in the formula. It is a viscous soluble fiber from the guar bean, and it does its work without ever being absorbed. In the small intestine it forms a gel that traps bile acids and slows the absorption of fats and sugars. When bile acids leave in the stool instead of being recycled, the liver must pull cholesterol out of the bloodstream to make more of them. Pooled analyses of randomized trials have consistently found that guar gum supplementation lowers total and LDL cholesterol. The gel also slows gastric emptying, which is why soluble fiber tends to blunt the post-meal glucose spike and increase the feeling of fullness.
Gugulipid is the standardized extract of Commiphora mukul, the mukul myrrh tree, and its active constituents are the plant sterols known as guggulsterones. These compounds interact with the farnesoid X receptor, a nuclear receptor that governs how the liver converts cholesterol into bile acids. Guggul has been used in Ayurvedic practice for lipid support for centuries. It is worth knowing that Western clinical trial results have been mixed, and Dr. Hirt includes it here for its traditional role and receptor-level mechanism as part of a combination rather than as a stand-alone agent.
Chromium rounds out the formula. It is an essential trace mineral involved in normal insulin action, and insulin resistance and abnormal lipids travel together so often that they define the metabolic syndrome. Reversol uses chromium polynicotinate, a niacin-bound form chosen for absorption. The 200 mcg serving supports the body's normal machinery for handling glucose and fat.
Taken together, Reversol offers nutritional support at the liver, in the intestine, and at the level of the metabolic hormones that tie them together. It is meant to work alongside a heart-healthy diet, regular movement, and periodic lipid testing.
Dosage:
Take two capsules twice daily with food, or as directed by Dr. Hirt. Because guar gum is a viscous fiber, take Reversol with a full glass of water and separate it by at least two hours from prescription medications.