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Real NAD+

Natural Pharmacy

Cellular Energy and Healthy Aging Support

A fast-melting sublingual tablet delivering NAD+ directly to bypass the digestive tract and first-pass metabolism. Designed to support mitochondrial energy production, DNA repair, sirtuin longevity pathways, and overall cellular vitality.

Suggested use: Take two to three tablets, once or twice daily, or as directed by Dr. Hirt. Allow each tablet to dissolve completely under the tongue rather than swallowing it. No water is necessary. If you are pregnant, nursing, or taking medication, review this with Dr. Hirt before starting.

May help with

Chronic FatigueJet LagFatigueBrain FogAgingAthletic Recovery

Key ingredients

  • NAD+
  • nicotinamide adenine dinucleotide

Product handout

Real NAD+

Cellular Energy and Healthy Aging Support

WHAT IT IS:

  • A fast-melting sublingual tablet delivering 300 mg of NAD+ (nicotinamide adenine dinucleotide), Earth’s universal and most usable form of energy

WHY YOU NEED IT:

  • Delivers NAD+ itself rather than a precursor, so no conversion step is required
  • Fast-melting sublingual delivery, designed to bypass the digestive tract and first-pass liver metabolism
  • NAD+ levels decline substantially with age and stress, and that decline is one of the most consistent findings in aging biology
  • Supports mitochondrial energy production, DNA repair enzymes, and the sirtuin longevity pathways
  • Great for patients with Jet Lag and Chronic Fatigue
  • An excellent oral companion between IV NAD+ infusions and NAD peptide injections
  • Popular with patients focused on energy, mental clarity, athletic recovery, and healthy aging
  • Gluten free, non-GMO, and manufactured in the USA
  • No water needed, so it is easy to take anywhere

HOW IT HELPS:

NAD+ is not a trendy molecule. It is one of the most fundamental coenzymes in human biochemistry, present in every cell you have. Its primary job is to carry electrons: it accepts the reducing power generated when you break down food and shuttles it to the mitochondria, where oxidative phosphorylation converts it into ATP, the currency your cells actually spend. Without adequate NAD+, energy production slows at the source.

NAD+ has a second job that has drawn intense scientific interest. It is the required substrate for two families of enzymes central to how cells age. The sirtuins depend on NAD+ to regulate gene expression, metabolic efficiency, and stress resistance. The PARP enzymes consume NAD+ while repairing damaged DNA. Both are, in effect, spending NAD+ to maintain the cell. When supply runs short, repair and regulation compete for the same limited pool.

The reason this matters clinically is that NAD+ availability declines with age. That decline has been documented across tissues and is now considered a contributor to the drop in mitochondrial efficiency, resilience, and repair capacity that accompanies aging. Preclinical work has shown that restoring NAD+ improves markers of metabolic, cardiovascular, neurological, and muscular function, and human trials of NAD+ precursors have demonstrated that blood and tissue NAD+ can be meaningfully raised by supplementation, with good tolerability at the doses studied.

Real NAD+ Plus takes a direct approach. This product supplies NAD+ itself, so no conversion step is required. The fast-melting sublingual tablet is designed to dissolve in the mouth and allow absorption through the oral mucosa, which bypasses digestion and first-pass liver metabolism. Preliminary human work on sublingual NAD+ delivery has reported substantial increases in whole-blood NAD+ over several weeks of daily use, and the sublingual route is an area of active research.

For patients already familiar with IV NAD+ or NAD peptide therapy, this is the practical daily companion. Infusions deliver a large dose at one moment in time; a sublingual tablet maintains steadier levels between visits.

Patients most often report improvements in daytime energy, mental clarity, and recovery from exercise. As with most nutritional interventions aimed at cellular metabolism, give it several weeks of consistent daily use before judging the result.

Dosage:

Take two to three tablets, once or twice daily, or as directed by Dr. Hirt. Allow each tablet to dissolve completely under the tongue rather than swallowing it. No water is necessary. If you are pregnant, nursing, or taking medication, review this with Dr. Hirt before starting.